Virus complement evasion strategies
نویسندگان
چکیده
منابع مشابه
Virus complement evasion strategies.
The immune system has a variety of tools at its disposal to combat virus infections. These can be subdivided roughly into two categories: 'first line defence', consisting of the non-specific, innate immune system, and 'adaptive immune response', acquired over time following virus infection or vaccination. During evolution, viruses have developed numerous, and often very ingenious, strategies to...
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Being a major first line of immune defense, the complement system keeps a constant vigil against viruses. Its ability to recognize large panoply of viruses and virus-infected cells, and trigger the effector pathways, results in neutralization of viruses and killing of the infected cells. This selection pressure exerted by complement on viruses has made them evolve a multitude of countermeasures...
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Finding factors that control complement (C) components deposition on bacterial cells is the way to explain the sophisticated mechanism of bacteraemia. Lipopolysaccharide (LPS, endotoxin) is a surface antigen found in the cell walls of Gram-negative bacteria, such as Salmonella [1]. LPS action on the human body is often considered in the context of sepsis, which is characterized by an excessive ...
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ژورنال
عنوان ژورنال: Journal of General Virology
سال: 2003
ISSN: 0022-1317,1465-2099
DOI: 10.1099/vir.0.18709-0